Polynucleotide Treatment in Birmingham
Clinician-led injectable skin treatment designed to support firmer, smoother, healthier-looking skin using advanced polynucleotides, including Vitaran for the face and Plinest for the under-eye area. Every treatment begins with a free in-person consultation at Hello Skin Clinic in Birmingham. Individual results may vary.
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What Are Polynucleotides?
Polynucleotides are highly purified DNA fragments, usually derived from salmon or trout DNA, that are biocompatible with human tissue. When carefully injected into the skin, they act as regenerative signals that help support fibroblast activity. Fibroblasts are the cells responsible for producing collagen and elastin, which play an important role in skin firmness, elasticity and overall skin quality.
Unlike dermal fillers, which add volume, or skin boosters such as Profhilo, which focus mainly on hydration, polynucleotides work by supporting the skin’s own repair processes. They do not change facial structure or create artificial volume. Instead, they help improve the appearance of skin quality gradually over a course of treatments.
At Hello Skin Clinic in Birmingham, we use Vitaran polynucleotides for facial skin rejuvenation and Plinest for the delicate under-eye area. Your clinician will assess your skin, concerns and goals during your consultation before recommending the most suitable treatment plan. Individual results may vary.
Polynucleotide Treatments — Face, Under Eyes & Hair
Polynucleotides for Face — Vitaran
Our facial polynucleotide treatments use Vitaran — a well-established product used widely across Europe for skin quality improvement. Vitaran is particularly suited to addressing fine lines, loss of firmness, and dull or uneven skin texture across the face, neck, and décolletage.
A typical course involves two to three sessions, spaced four weeks apart, with visible changes in skin quality developing gradually over six to eight weeks as the regenerative process builds.
Polynucleotides for Under Eyes — Plinest
The under-eye area is one of the most requested treatment zones for polynucleotides — and one of the most technically demanding. We use Plinest specifically for this area, chosen for its fine formulation that makes it suitable for the thin, delicate skin beneath the eyes.
Polynucleotides around the eye area may help with the appearance of hollowness, fine lines, and skin crepiness that can make the eyes look tired. This is a gradual process — results typically become noticeable from four to six weeks after the first session.
Polynucleotides for Hair — Nucleofill
We also offer Nucleofill polynucleotide scalp treatments as part of our hair restoration programme — supporting scalp health and hair follicle environment as a complement to PRP hair therapy. Ask about this during your consultation.
What to Expect at Your Polynucleotide Appointment
Step 1:
Free In-Person Consultation
Every polynucleotide treatment at Hello Skin Clinic begins with a free in-person consultation. Your clinician will assess your skin, discuss your concerns and goals, and recommend the most appropriate product and treatment plan for you. There is no obligation to proceed.
Step 2
Treatment Preparation
Before your treatment, the area is cleansed and prepared to clinical standards. A topical numbing cream may be applied to help minimise discomfort, depending on the treatment area. Your clinician will explain each step clearly so you feel informed and comfortable before treatment begins.
Step 3
Polynucleotide Injections
Polynucleotides are administered using a series of small, precise injections into the selected treatment area. The number of injection points depends on whether you are treating the face, under eyes, neck, décolletage or scalp. Most clients describe the treatment as mild and manageable.
Step 4
Aftercare and Recovery
There is usually minimal downtime after polynucleotide treatment. Mild redness, swelling, tenderness or small bumps at the injection points can occur and usually settle within 24 to 48 hours. Your clinician will provide full aftercare guidance, including what to avoid after treatment and how to support your skin during recovery.
Step 5
Results Over Time
Polynucleotides work gradually by supporting the skin’s natural repair processes. Unlike dermal fillers, they do not create instant volume or a dramatic immediate change. Improvements in skin quality, firmness, hydration and texture may develop over several weeks, with many clients completing a course of two to three sessions depending on their treatment plan. Individual results may vary.
Polynucleotides vs Profhilo: What Is the Difference?
Polynucleotides and Profhilo are both injectable skin treatments used to improve skin quality, but they work in different ways and are suited to different concerns.
Profhilo is made with a high concentration of hyaluronic acid. It spreads beneath the skin to support hydration, elasticity and skin firmness through a process known as bio-remodelling. Profhilo is often recommended for clients concerned with overall skin laxity, dehydration, crepey skin and loss of skin density.
Polynucleotides are made from purified DNA fragments that support the skin’s natural repair processes. Instead of mainly focusing on hydration, polynucleotides work gradually by supporting fibroblast activity, collagen production and tissue regeneration. They may be especially useful for targeted concerns such as under-eye skin quality, fine lines, dullness, loss of firmness and delicate areas where other injectables may not be suitable.
Profhilo is often chosen for wider areas of skin hydration and laxity, while polynucleotides are often chosen for more targeted skin regeneration and delicate treatment areas. In some cases, your clinician may recommend both treatments as part of a personalised skin rejuvenation plan.
At Hello Skin Clinic in Birmingham, every treatment begins with a free in-person consultation. Your clinician will assess your skin, discuss your goals and recommend the most suitable option based on your concerns, skin condition and treatment suitability. Individual results may vary.
Polynucleotide Treatment: Frequently Asked Questions
What are polynucleotides used for?
Polynucleotides are used to support skin quality, hydration, firmness, elasticity and overall skin regeneration. They are commonly used on the face, under-eye area, neck, décolletage and, in some cases, the scalp as part of a wider hair and skin support plan. At Hello Skin Clinic in Birmingham, your clinician will assess your concerns before recommending the most suitable product and treatment area.
How long do polynucleotides take to work?
Polynucleotides work gradually. Some clients may begin to notice improvements in skin hydration and texture within a few weeks, but more visible changes usually develop over four to eight weeks as the skin’s repair processes progress. Results vary depending on the treatment area, skin condition, number of sessions and individual response.
How long do polynucleotides last?
The longevity of polynucleotide results varies from person to person. Many clients complete an initial course of two to three sessions, followed by maintenance treatments when recommended by their clinician. Factors such as age, skin quality, lifestyle, treatment area and aftercare can all affect how long results are maintained.
Do polynucleotides work?
Polynucleotides may help improve the appearance of skin quality, firmness, hydration, fine lines and texture when used as part of a suitable treatment plan. They do not create instant volume like dermal fillers. Instead, they support gradual skin regeneration over time. Suitability and expected outcomes are discussed during your free in-person consultation.
What are the side effects of polynucleotides?
Common temporary effects may include redness, mild swelling, tenderness, bruising or small bumps at the injection points. These usually settle within 24 to 48 hours, although this can vary depending on the treatment area and individual response. More serious side effects are uncommon but will be discussed during your consultation before treatment.
Can polynucleotides go wrong?
As with any injectable treatment, there are potential risks if polynucleotides are not administered correctly or if the treatment is unsuitable for the client. This is why it is important to choose a trained practitioner and have a proper consultation before treatment. At Hello Skin Clinic, your clinician will assess your skin, medical history, allergies and goals before recommending treatment.
What is the aftercare for polynucleotides?
After polynucleotide treatment, you should avoid touching or massaging the treated area for at least 24 hours. You may also be advised to avoid makeup, alcohol, strenuous exercise, saunas, steam rooms and active skincare for a short period after treatment. Your clinician will provide personalised aftercare instructions based on the area treated.
How much does polynucleotide treatment cost in Birmingham?
The cost of polynucleotide treatment in Birmingham depends on the area being treated, the product used and the number of sessions recommended. Treatments such as Vitaran for the face, Plinest for under eyes and Nucleofill for hair or scalp support may be priced differently. At Hello Skin Clinic, your exact treatment plan and quotation are confirmed during your free in-person consultation.
Dos and Don’ts Before and After Polynucleotide Treatment
Before Your Appointment
Do’s
Drink plenty of water in the days leading up to your appointment to help keep your skin well hydrated.
Inform your clinician about any allergies, especially fish allergies, as well as any medication, supplements or medical conditions.
Eat a light meal before your session to help you feel comfortable during treatment.
Arrive with clean skin and avoid wearing heavy makeup on the treatment area where possible.
Don’ts
Do not drink alcohol for at least 24 hours before treatment, as this may increase the risk of bruising.
Avoid active skincare ingredients such as retinol, exfoliating acids or strong vitamin C for 48 hours before your appointment.
Do not book treatment if you have an active skin infection, cold sore, open wound or irritation in the treatment area.
Avoid other intensive skin treatments in the same area unless your clinician has advised it is safe.
After Your Appointment
Do’s
Keep the treated area clean and avoid unnecessary touching.
Use a gentle cold compress if you experience mild swelling or tenderness.
Stay hydrated and follow the aftercare advice provided by your clinician.
Use gentle skincare and apply SPF daily to protect your skin while it settles.
Don’ts
Do not touch, rub or massage the treated area for at least 24 hours.
Avoid strenuous exercise, saunas, steam rooms and excessive heat for 48 hours.
Do not apply makeup to the treated area for 12 to 24 hours, unless advised otherwise.
Avoid alcohol and caffeine for 24 hours after treatment to help minimise swelling and bruising.
Do not use retinol, exfoliating acids or strong active skincare until your clinician advises it is safe to restart.
What Our Birmingham Clients Say
Real feedback from clients who visited Hello Skin Clinic for advanced skin, aesthetic and wellness treatments. Individual experiences and results may vary.
Meet The Team
Tekla
Tekla is the Director of Hello Skin Clinic and our resident skin expert. As a Level 7 Aesthetics Practitioner with over five years of experience, she specialises in advanced skin and aesthetic treatments, including laser therapies, injectable treatments, skin rejuvenation and targeted fat reduction.
Tekla takes a personalised, consultation-led approach to every treatment, helping clients feel informed, comfortable and confident throughout their journey at Hello Skin Clinic.
About Hello Skin Clinic
At Hello Skin Clinic, we offer a luxurious, relaxing environment while delivering exceptional results for our clients.
If you’re considering polynucleotides in Birmingham, Hello Skin Clinic may be the solution for you. Our experienced aesthetic practitioners begin your treatment with a comprehensive consultation, ensuring every procedure is perfectly tailored to achieve beautiful, natural results just for you.
How to Find Us
Visit us in our luxury Birmingham City Centre clinic, conveniently located a short walk from Brindley Place.
Parking is available on street near the clinic, or at the Arena Birmingham – South car park just a minute’s walk away.
We strive to provide a luxurious, relaxing environment for all our clients. That’s why our clinic is rated five stars by our customers on Google. So get in touch today to find out why we are the clinic of choice for Polynucleotides in Birmingham!